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Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity

The centrosome plays an important role in maintenance of cell polarity and in progression through the cell cycle by determining the number, polarity, and organization of interphase and mitotic microtubules. By examining a set of 35 high grade human breast tumors, we show that centrosomes of adenocar...

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Autors principals: Lingle, Wilma L., Lutz, Ward H., Ingle, James N., Maihle, Nita J., Salisbury, Jeffrey L.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19675/
https://ncbi.nlm.nih.gov/pubmed/9501196
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