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Dislocation of a Type I Membrane Protein Requires Interactions between Membrane-spanning Segments within the Lipid Bilayer

The human cytomegalovirus gene product US11 causes rapid degradation of class I major histocompatibility complex (MHCI) heavy chains by inducing their dislocation from the endoplasmic reticulum (ER) and subsequent degradation by the proteasome. This set of reactions resembles the endogenous cellular...

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Pubblicato in:Mol Biol Cell
Autori principali: Lilley, Brendan N., Tortorella, Domenico, Ploegh, Hidde L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196560/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12972557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-03-0192
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