Loading...

Dislocation of a Type I Membrane Protein Requires Interactions between Membrane-spanning Segments within the Lipid Bilayer

The human cytomegalovirus gene product US11 causes rapid degradation of class I major histocompatibility complex (MHCI) heavy chains by inducing their dislocation from the endoplasmic reticulum (ER) and subsequent degradation by the proteasome. This set of reactions resembles the endogenous cellular...

Full description

Saved in:
Bibliographic Details
Main Authors: Lilley, Brendan N., Tortorella, Domenico, Ploegh, Hidde L.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC196560/
https://ncbi.nlm.nih.gov/pubmed/12972557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-03-0192
Tags: Add Tag
No Tags, Be the first to tag this record!