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Spy1 Interacts with p27(Kip1) to Allow G(1)/S Progression
Progression through the G(1)/S transition commits cells to synthesize DNA. Cyclin dependent kinase 2 (CDK2) is the major kinase that allows progression through G(1)/S phase and subsequent replication events. p27 is a CDK inhibitor (CKI) that binds to CDK2 to prevent premature activation of this kina...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196558/ https://ncbi.nlm.nih.gov/pubmed/12972555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-12-0820 |
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