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Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure

The role of the tumor suppressor retinoblastoma protein (pRb) has been firmly established in the control of cell cycle, apoptosis, and differentiation. Recently, it was demonstrated that lack of pRb promotes a switch from white to brown adipocyte differentiation in vitro. We used the Cre-Lox system...

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Main Authors: Dali-Youcef, Nassim, Mataki, Chikage, Coste, Agnès, Messaddeq, Nadia, Giroud, Sylvain, Blanc, Stéphane, Koehl, Christian, Champy, Marie-France, Chambon, Pierre, Fajas, Lluis, Metzger, Daniel, Schoonjans, Kristina, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965576/
https://ncbi.nlm.nih.gov/pubmed/17556545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611568104
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