Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure

The role of the tumor suppressor retinoblastoma protein (pRb) has been firmly established in the control of cell cycle, apoptosis, and differentiation. Recently, it was demonstrated that lack of pRb promotes a switch from white to brown adipocyte differentiation in vitro. We used the Cre-Lox system...

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Detalles Bibliográficos
Autores principales: Dali-Youcef, Nassim, Mataki, Chikage, Coste, Agnès, Messaddeq, Nadia, Giroud, Sylvain, Blanc, Stéphane, Koehl, Christian, Champy, Marie-France, Chambon, Pierre, Fajas, Lluis, Metzger, Daniel, Schoonjans, Kristina, Auwerx, Johan
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965576/
https://ncbi.nlm.nih.gov/pubmed/17556545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611568104
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