Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure

The role of the tumor suppressor retinoblastoma protein (pRb) has been firmly established in the control of cell cycle, apoptosis, and differentiation. Recently, it was demonstrated that lack of pRb promotes a switch from white to brown adipocyte differentiation in vitro. We used the Cre-Lox system...

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Detalhes bibliográficos
Main Authors: Dali-Youcef, Nassim, Mataki, Chikage, Coste, Agnès, Messaddeq, Nadia, Giroud, Sylvain, Blanc, Stéphane, Koehl, Christian, Champy, Marie-France, Chambon, Pierre, Fajas, Lluis, Metzger, Daniel, Schoonjans, Kristina, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965576/
https://ncbi.nlm.nih.gov/pubmed/17556545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611568104
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