Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure

The role of the tumor suppressor retinoblastoma protein (pRb) has been firmly established in the control of cell cycle, apoptosis, and differentiation. Recently, it was demonstrated that lack of pRb promotes a switch from white to brown adipocyte differentiation in vitro. We used the Cre-Lox system...

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Bibliografische gegevens
Hoofdauteurs: Dali-Youcef, Nassim, Mataki, Chikage, Coste, Agnès, Messaddeq, Nadia, Giroud, Sylvain, Blanc, Stéphane, Koehl, Christian, Champy, Marie-France, Chambon, Pierre, Fajas, Lluis, Metzger, Daniel, Schoonjans, Kristina, Auwerx, Johan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965576/
https://ncbi.nlm.nih.gov/pubmed/17556545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611568104
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