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Acute stress increases interstitial fluid amyloid-β via corticotropin-releasing factor and neuronal activity
Aggregation of the amyloid-β (Aβ) peptide in the extracellular space of the brain is critical in the pathogenesis of Alzheimer's disease. Aβ is produced by neurons and released into the brain interstitial fluid (ISF), a process regulated by synaptic activity. To determine whether behavioral str...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965571/ https://ncbi.nlm.nih.gov/pubmed/17551018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700148104 |
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