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The intracellular region of Notch ligands: does the tail make the difference?
The cytoplasmic tail of Notch ligands drives endocytosis, mediates association with proteins implicated in the organization of cell-cell junctions and, through regulated intra-membrane proteolysis, is released from the membrane as a signaling fragment. We survey these findings and discuss the role o...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965462/ https://ncbi.nlm.nih.gov/pubmed/17623096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-2-19 |
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