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The intracellular region of Notch ligands: does the tail make the difference?

The cytoplasmic tail of Notch ligands drives endocytosis, mediates association with proteins implicated in the organization of cell-cell junctions and, through regulated intra-membrane proteolysis, is released from the membrane as a signaling fragment. We survey these findings and discuss the role o...

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Hlavní autoři: Pintar, Alessandro, De Biasio, Alfredo, Popovic, Matija, Ivanova, Neli, Pongor, Sándor
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965462/
https://ncbi.nlm.nih.gov/pubmed/17623096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-2-19
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