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A Monomeric Membrane Peptide that Lives in Three Worlds: In Solution, Attached to, and Inserted across Lipid Bilayers

The membrane peptide pH (low) insertion peptide (pHLIP) lives in three worlds, being soluble in aqueous solution at pH 7.4, binding to the surface of lipid bilayers, and inserting as a transbilayer helix at low pH. With low pH driving the process, pHLIP can translocate cargo molecules attached to it...

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Autori principali: Reshetnyak, Yana K., Segala, Michael, Andreev, Oleg A., Engelman, Donald M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965453/
https://ncbi.nlm.nih.gov/pubmed/17557792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109967
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