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Identification of an activation region in the proteasome activator REGα

Proteasomes can be markedly activated by associating with 19S regulatory complexes to form the 26S protease or by binding 11S protein complexes known as REG or PA28. Three REG subunits, α, β, and γ, have been expressed in Escherichia coli, and each recombinant protein can activate human proteasomes....

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Главные авторы: Zhang, Zhiguo, Clawson, Andrew, Realini, Claudio, Jensen, Christopher C., Knowlton, J. Randolph, Hill, Christopher P., Rechsteiner, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC19650/
https://ncbi.nlm.nih.gov/pubmed/9501171
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