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Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

BACKGROUND: The Down syndrome phenotype has been attributed to overexpression of chromosome 21 (Hsa21) genes. However, the expression profile of Hsa21 genes in trisomic human subjects as well as their effects on genes located on different chromosomes are largely unknown. Using oligonucleotide microa...

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Detalhes bibliográficos
Main Authors: Conti, Anna, Fabbrini, Floriana, D'Agostino, Paola, Negri, Rosa, Greco, Dario, Genesio, Rita, D'Armiento, Maria, Olla, Carlo, Paladini, Dario, Zannini, Mariastella, Nitsch, Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964766/
https://ncbi.nlm.nih.gov/pubmed/17683628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-268
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