Carbon dioxide stimulates peroxynitrite-mediated nitration of tyrosine residues and inhibits oxidation of methionine residues of glutamine synthetase: Both modifications mimic effects of adenylylation

Eitemau Tebyg

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• Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentration: pH dependence of carbonyl formation, tyrosine nitration, and methionine oxidation
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• Methionine residues as endogenous antioxidants in proteins
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• Ability of Nonenzymic Nitration or Acetylation of E. coli Glutamine Synthetase to Produce Effects Analogous to Enzymic Adenylylation
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• Regulation of synthesis of glutamine synthetase by adenylylated glutamine synthetase.
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