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Epigenetics, mismatch repair genes and colorectal cancer.

The recent discovery of hypermethylation of the promoter of genes is a powerful epigenetic mechanism for the inactivation of tumour suppressor genes in colorectal and other cancers. Approximately 95% of hereditary non-polyposis colorectal cancers (HNPCCs) and 15% of sporadic colorectal cancers (CRCs...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Wheeler, J. M. D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Royal College of Surgeons of England 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1963859/
https://ncbi.nlm.nih.gov/pubmed/15720901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1308/1478708051423
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