Association between family history and mismatch repair in colorectal cancer

Background and aims: Germline mutations in mismatch repair (MMR) genes cause a greatly increased risk of cancer of the gastrointestinal and female reproductive tracts (hereditary non-polyposis colorectal cancer (HNPCC)). Loss of MMR expression is common in colorectal cancer (CRC) overall. Such loss...

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Detalhes bibliográficos
Main Authors: Coggins, R P, Cawkwell, L, Bell, S M, Crockford, G P, Quirke, P, Finan, P J, Bishop, D T
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Gut 2005
Assuntos:
Colorectal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774492/
https://ncbi.nlm.nih.gov/pubmed/15831908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.017517
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