MitoNEET is a uniquely folded 2Fe–2S outer mitochondrial membrane protein stabilized by pioglitazone

Iron–sulfur (Fe–S) proteins are key players in vital processes involving energy homeostasis and metabolism from the simplest to most complex organisms. We report a 1.5 Å x-ray crystal structure of the first identified outer mitochondrial membrane Fe–S protein, mitoNEET. Two protomers intertwine to f...

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Detalhes bibliográficos
Main Authors: Paddock, Mark L., Wiley, Sandra E., Axelrod, Herbert L., Cohen, Aina E., Roy, Melinda, Abresch, Edward C., Capraro, Dominique, Murphy, Anne N., Nechushtai, Rachel, Dixon, Jack E., Jennings, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1963346/
https://ncbi.nlm.nih.gov/pubmed/17766440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707189104
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