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Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

The Drosophila insulin receptor (dInR) regulates cell growth and proliferation through the dPI3K/dAkt pathway, which is conserved in metazoan organisms. Here we report the identification and functional characterization of the Drosophila forkhead-related transcription factor dFOXO, a key component of...

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Hlavní autoři: Puig, Oscar, Marr, Michael T., Ruhf, M. Laure, Tjian, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC196255/
https://ncbi.nlm.nih.gov/pubmed/12893776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1098703
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