Nalaganje...
Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells
To dissect apoptotic genes governing the survival of colorectal carcinoma cells, we employed RNAi to silence Bcl-2 and Bcl-x(L) in isogenic clones of p53+/+ and p53−/− cells, and of Bax+/− and Bax−/− cells. We identify a novel proapoptotic function of p53 that does not require activation by genotoxi...
Shranjeno v:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2003
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196025/ https://ncbi.nlm.nih.gov/pubmed/12670866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252603 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|