Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance
A Cre/lox-conditional mouse line was generated to evaluate the role of ATR in checkpoint responses to ionizing radiation (IR) and stalled DNA replication. We demonstrate that after IR treatment, ATR and ATM each contribute to early delay in M-phase entry but that ATR regulates a majority of the late...
Sparad:
| I publikationen: | Genes Dev |
|---|---|
| Huvudupphov: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Cold Spring Harbor Laboratory Press
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12629044/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1067403 |
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