Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-α-phenylnitrone

According to the free radical theory of aging, reactive oxygen species cause oxidative damage, proposed to be an underlying factor of the aging process. In the current study, we have used electron paramagnetic resonance spin labeling, measurements of protein carbonyl content, an index of protein oxi...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Butterfield, D. Allan, Howard, Beverly J., Yatin, Servet, Allen, Kerry L., Carney, John M.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1997
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.674
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