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BAP-135, a target for Bruton’s tyrosine kinase in response to B cell receptor engagement

Bruton’s tyrosine kinase (Btk) is essential for B cell activation, but downstream targets of Btk have not been defined. We now describe a protein, BAP-135, that is associated with Btk in B cells and is a substrate for phosphorylation by Btk. BAP-135, which exhibits no detectable homology to known pr...

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Autors principals: Yang, Weiyi, Desiderio, Stephen
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19560/
https://ncbi.nlm.nih.gov/pubmed/9012831
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