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Metabolic engineering of a genetic selection system with tunable stringency
The biosynthesis of small molecules can be fine-tuned by (re)engineering metabolic flux within cells. We have adapted this approach to optimize an in vivo selection system for the conversion of prephenate to phenylpyruvate, a key step in the production of the essential aromatic amino acid phenylalan...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1955800/ https://ncbi.nlm.nih.gov/pubmed/17715291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705379104 |
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