Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease

BACKGROUND/AIM: Interleukin 31 (IL31), primarily expressed in activated lymphocytes, signals through a heterodimeric receptor complex consisting of the IL31 receptor alpha (IL31Rα) and the oncostatin M receptor (OSMR). The aim of this study was to analyse IL31 receptor expression, signal transductio...

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Autori principali: Dambacher, Julia, Beigel, Florian, Seiderer, Julia, Haller, Dirk, Göke, Burkhard, Auernhammer, Christoph J, Brand, Stephan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2007
Soggetti:
Inflammatory Bowel Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954980/
https://ncbi.nlm.nih.gov/pubmed/17449633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.118679
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