Oncostatin M Mediates STAT3-Dependent Intestinal Epithelial Restitution via Increased Cell Proliferation, Decreased Apoptosis and Upregulation of SERPIN Family Members

OBJECTIVE: Oncostatin M (OSM) is produced by activated T cells, monocytes, and dendritic cells and signals through two distinct receptor complexes consisting of gp130 and LIFR (I) or OSMR-β and gp130 (II), respectively. Aim of this study was to analyze the role of OSM in intestinal epithelial cells...

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Detalhes bibliográficos
Main Authors: Beigel, Florian, Friedrich, Matthias, Probst, Corina, Sotlar, Karl, Göke, Burkhard, Diegelmann, Julia, Brand, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977870/
https://ncbi.nlm.nih.gov/pubmed/24710357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093498
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