G protein‐coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate‐induced colitis in mice

BACKGROUND: Infiltration of inflammatory cells into the colon plays an important role in the onset and course of inflammatory bowel disease. G‐protein‐coupled receptor kinase 6 (GRK6) is an intracellular kinase that regulates the sensitivity of certain G‐protein‐coupled receptors, including those in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eijkelkamp, Niels, Heijnen, Cobi J, Lucas, Ayscha, Premont, Richard T, Elsenbruch, Sigrid, Schedlowski, Manfred, Kavelaars, Annemieke
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2007
Schlagworte:
Colon
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954868/
https://ncbi.nlm.nih.gov/pubmed/17229795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.107094
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