G protein-coupled receptor kinase 2 positively regulates epithelial cell migration

Cell migration requires integration of signals arising from both the extracellular matrix and messengers acting through G protein-coupled receptors (GPCRs). We find that increased levels of G protein-coupled receptor kinase 2 (GRK2), a key player in GPCR regulation, potentiate migration of epithelia...

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Main Authors: Penela, Petronila, Ribas, Catalina, Aymerich, Ivette, Eijkelkamp, Niels, Barreiro, Olga, Heijnen, Cobi J, Kavelaars, Annemieke, Sánchez-Madrid, Francisco, Mayor, Federico
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367399/
https://ncbi.nlm.nih.gov/pubmed/18369319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.55
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