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The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning
Anterior-posterior (A/P) limb patterning in vertebrates is determined by the counteraction between the Sonic Hedgehog (Shh) and the Gli3 transcription factor. Shh exerts its effect on Gli3 by regulating the full-length Gli3 protein processing to generate a Gli3 repressor gradient along the A/P axis...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952533/ https://ncbi.nlm.nih.gov/pubmed/17400206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.02.029 |
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