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Crystallographic analysis of murine constitutive androstane receptor ligand-binding domain complexed with 5α-androst-16-en-3α-ol

The constitutive androstane receptor (CAR) is a member of the nuclear receptor superfamily. In contrast to classical nuclear receptors, which possess small-molecule ligand-inducible activity, CAR exhibits constitutive transcriptional activity in the apparent absence of ligand. CAR is among the most...

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Autori principali: Vincent, Jeremy, Shan, Li, Fan, Ming, Brunzelle, Joseph S., Forman, Barry M., Fernandez, Elias J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952403/
https://ncbi.nlm.nih.gov/pubmed/16508121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309104032762
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