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Expression, purification, crystallization and preliminary crystallographic analysis of human Pim-­1 kinase

Pim kinases, including Pim-1, Pim-2 and Pim-3, belong to a distinctive serine/threonine protein-kinase family. They are involved in cytokine-induced signal transduction and the development of lymphoid malignancies. Their kinase domains are highly homologous to one another, but share low sequence ide...

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Detalhes bibliográficos
Main Authors: Qian, Kevin C., Studts, Joey, Wang, Lian, Barringer, Kevin, Kronkaitis, Anthony, Peng, Charline, Baptiste, Alistair, LaFrance, Roger, Mische, Sheenah, Farmer, Bennett
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952393/
https://ncbi.nlm.nih.gov/pubmed/16508102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309104029963
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