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Ribosomal Protein L33 Is Required for Ribosome Biogenesis, Subunit Joining, and Repression of GCN4 Translation

We identified a mutation in the 60S ribosomal protein L33A (rpl33a-G76R) that elicits derepression of GCN4 translation (Gcd(−) phenotype) by allowing scanning preinitiation complexes to bypass inhibitory upstream open reading frame 4 (uORF4) independently of prior uORF1 translation and reinitiation....

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Detalhes bibliográficos
Main Authors: Martín-Marcos, Pilar, Hinnebusch, Alan G., Tamame, Mercedes
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952170/
https://ncbi.nlm.nih.gov/pubmed/17548477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00019-07
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