Mucosal Immunization with a Novel Nanoemulsion-Based Recombinant Anthrax Protective Antigen Vaccine Protects against Bacillus anthracis Spore Challenge

The currently available commercial human anthrax vaccine requires multiple injections for efficacy and has side effects due to its alum adjuvant. These factors limit its utility when immunizing exposed populations in emergent situations. We evaluated a novel mucosal adjuvant that consists of a nonto...

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Bibliographic Details
Main Authors: Bielinska, Anna U., Janczak, Katarzyna W., Landers, Jeffrey J., Makidon, Paul, Sower, Laurie E., Peterson, Johnny W., Baker, James R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952013/
https://ncbi.nlm.nih.gov/pubmed/17502384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00070-07
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