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Checkpoint Blockade in Cancer Immunotherapy

The progression of a productive immune response requires that a number of immunological checkpoints be passed. Passage may require the presence of excitatory costimulatory signals or the avoidance of negative or coinhibitory signals, which act to dampen or terminate immune activity. The immunoglobul...

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Detalles Bibliográficos
Main Authors: Korman, Alan J., Peggs, Karl S., Allison, James P.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951510/
https://ncbi.nlm.nih.gov/pubmed/16730267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-2776(06)90008-X
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