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Checkpoint Blockade in Cancer Immunotherapy

The progression of a productive immune response requires that a number of immunological checkpoints be passed. Passage may require the presence of excitatory costimulatory signals or the avoidance of negative or coinhibitory signals, which act to dampen or terminate immune activity. The immunoglobul...

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Autors principals: Korman, Alan J., Peggs, Karl S., Allison, James P.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951510/
https://ncbi.nlm.nih.gov/pubmed/16730267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-2776(06)90008-X
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