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Regulation of P-TEFb Elongation Complex Activity by CDK9 Acetylation
P-TEFb, comprised of CDK9 and a cyclin T subunit, is a global transcriptional elongation factor important for most RNA polymerase II (pol II) transcription. P-TEFb facilitates transcription elongation in part by phosphorylating Ser2 of the heptapeptide repeat of the carboxy-terminal domain (CTD) of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1951478/ https://ncbi.nlm.nih.gov/pubmed/17452463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00857-06 |
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