Evidence of Endogenous Mu Opioid Receptor Regulation by Epigenetic Control of the Promoters

The pharmacological effect of morphine as a painkiller is mediated mainly via the mu opioid receptor (MOR) and is dependent on the number of MORs in the cell surface membrane. While several studies have reported that the MOR gene is regulated by various cis- and trans-acting factors, many questions...

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Main Authors: Hwang, Cheol Kyu, Song, Kyu Young, Kim, Chun Sung, Choi, Hack Sun, Guo, Xiao-Hong, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951474/
https://ncbi.nlm.nih.gov/pubmed/17452465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00073-07
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