Epigenetic programming of μ-opioid receptor gene in mouse brain is regulated by MeCP2 and brg1 chromatin remodelling factor

The pharmacological action of morphine as a pain medication is mediated primarily through the μ-opioid receptor (MOR). With few exceptions, MOR is expressed in brain regions where opioid actions take place. The basis for this unique spatial expression of MOR remains undetermined. Recently, we report...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Hwang, Cheol Kyu, Song, Kyu Young, Kim, Chun Sung, Choi, Hack Sun, Guo, Xiao-Hong, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2009
Schlagworte:
Epigenetic Control
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516510/
https://ncbi.nlm.nih.gov/pubmed/19602036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00535.x
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