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Up-Regulation of the μ-Opioid Receptor Gene Is Mediated through Chromatin Remodeling and Transcriptional Factors in Differentiated Neuronal Cells

The effects of morphine are mediated mainly through the μ opioid receptor (MOR). Expression of the MOR is up-regulated during neuronal differentiation in P19 embryonal carcinoma cells and epigenetic changes play an important role in MOR up-regulation. This study investigates the basis for differenti...

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Detaylı Bibliyografya
Asıl Yazarlar: Hwang, Cheol Kyu, Kim, Chun Sung, Kim, Do Kyung, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912061/
https://ncbi.nlm.nih.gov/pubmed/20385708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.064311
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