Evidence of Endogenous Mu Opioid Receptor Regulation by Epigenetic Control of the Promoters

The pharmacological effect of morphine as a painkiller is mediated mainly via the mu opioid receptor (MOR) and is dependent on the number of MORs in the cell surface membrane. While several studies have reported that the MOR gene is regulated by various cis- and trans-acting factors, many questions...

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Bibliographic Details
Main Authors: Hwang, Cheol Kyu, Song, Kyu Young, Kim, Chun Sung, Choi, Hack Sun, Guo, Xiao-Hong, Law, Ping-Yee, Wei, Li-Na, Loh, Horace H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951474/
https://ncbi.nlm.nih.gov/pubmed/17452465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00073-07
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