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Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress

Hepatic steatosis is a common histological feature of chronic hepatitis C. Hepatitis C virus (HCV) gene expression has been shown to alter host cell cholesterol/lipid metabolism and thus induce hepatic steatosis. Since sterol regulatory element binding proteins (SREBPs) are major regulators of lipid...

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מידע ביבליוגרפי
Main Authors: Waris, Gulam, Felmlee, Daniel Jeffery, Negro, Francesco, Siddiqui, Aleem
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951320/
https://ncbi.nlm.nih.gov/pubmed/17507484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00125-07
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