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Identification of Two Distinct Human Immunodeficiency Virus Type 1 Vif Determinants Critical for Interactions with Human APOBEC3G and APOBEC3F
Human cytidine deaminases APOBEC3G (A3G) and APOBEC3F (A3F) inhibit replication of Vif-deficient human immunodeficiency virus type 1 (HIV-1). HIV-1 Vif overcomes these host restriction factors by binding to them and inducing their proteasomal degradation. The Vif-A3G and Vif-A3F interactions are att...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1951317/ https://ncbi.nlm.nih.gov/pubmed/17522216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00395-07 |
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