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Hepatitis C Virus Envelope Glycoprotein E2 Glycans Modulate Entry, CD81 Binding, and Neutralization

Hepatitis C virus (HCV) is a major human pathogen that causes serious liver disease, including cirrhosis and hepatocellular carcinoma. The primary target cells of HCV are hepatocytes, and entry is restricted by interactions of the envelope glycoproteins, E1 and E2, with cellular receptors. E1 and E2...

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Detalles Bibliográficos
Main Authors: Falkowska, Emilia, Kajumo, Francis, Garcia, Edie, Reinus, John, Dragic, Tatjana
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951298/
https://ncbi.nlm.nih.gov/pubmed/17507469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00459-07
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