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Identification of the Optimal DC-SIGN Binding Site on Human Immunodeficiency Virus Type 1 gp120

Human immunodeficiency virus type 1 (HIV-1) envelope (gp120) binding to DC-SIGN, a C-type lectin that can facilitate HIV infection in cis and in trans, is largely dependent on high-mannose-content moieties. Here, we delineate the N-linked glycosylation (N-glycan) sites in gp120 that contribute to op...

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Detalhes bibliográficos
Main Authors: Hong, Patrick W.-P., Nguyen, Sandra, Young, Sophia, Su, Stephen V., Lee, Benhur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951277/
https://ncbi.nlm.nih.gov/pubmed/17522223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01765-06
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