Lipopolysaccharide Analogs Improve Efficacy of Acellular Pertussis Vaccine and Reduce Type I Hypersensitivity in Mice

Pertussis is an infectious disease of the respiratory tract that is caused by the gram-negative bacterium Bordetella pertussis. Although acellular pertussis (aP) vaccines are safe, they are not fully effective and thus require improvement. In contrast to whole-cell pertussis (wP) vaccines, aP vaccin...

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Detalhes bibliográficos
Main Authors: Geurtsen, Jeroen, Banus, H. Alexander, Gremmer, Eric R., Ferguson, Henke, de la Fonteyne-Blankestijn, Liset J. J., Vermeulen, Jolanda P., Dormans, Jan A. M. A., Tommassen, Jan, van der Ley, Peter, Mooi, Frits R., Vandebriel, Rob J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951065/
https://ncbi.nlm.nih.gov/pubmed/17494641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00074-07
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