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Case-Control Association Testing with Related Individuals: A More Powerful Quasi-Likelihood Score Test

We consider the problem of genomewide association testing of a binary trait when some sampled individuals are related, with known relationships. This commonly arises when families sampled for a linkage study are included in an association study. Furthermore, power to detect association with complex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thornton, Timothy , McPeek, Mary Sara 
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Human Genetics 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950805/
https://ncbi.nlm.nih.gov/pubmed/17668381
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