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ROADTRIPS: Case-Control Association Testing with Partially or Completely Unknown Population and Pedigree Structure
Genome-wide association studies are routinely conducted to identify genetic variants that influence complex disorders. It is well known that failure to properly account for population or pedigree structure can lead to spurious association as well as reduced power. We propose a method, ROADTRIPS, for...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820184/ https://ncbi.nlm.nih.gov/pubmed/20137780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.01.001 |
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