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An Incomplete-Data Quasi-likelihood Approach to Haplotype-Based Genetic Association Studies on Related Individuals

We propose an incomplete-data, quasi-likelihood framework, for estimation and score tests, which accommodates both dependent and partially-observed data. The motivation comes from genetic association studies, where we address the problems of estimating haplotype frequencies and testing association b...

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Bibliografiske detaljer
Main Authors: Wang, Zuoheng, McPeek, Mary Sara
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860453/
https://ncbi.nlm.nih.gov/pubmed/20428335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1198/jasa.2009.tm08507
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