Mutations in Cardiac T-Box Factor Gene TBX20 Are Associated with Diverse Cardiac Pathologies, Including Defects of Septation and Valvulogenesis and Cardiomyopathy

The T-box family transcription factor gene TBX20 acts in a conserved regulatory network, guiding heart formation and patterning in diverse species. Mouse Tbx20 is expressed in cardiac progenitor cells, differentiating cardiomyocytes, and developing valvular tissue, and its deletion or RNA interferen...

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Main Authors: Kirk, Edwin P. , Sunde, Margaret , Costa, Mauro W. , Rankin, Scott A. , Wolstein, Orit , Castro, M. Leticia , Butler, Tanya L. , Hyun, Changbaig , Guo, Guanglan , Otway, Robyn , Mackay, Joel P. , Waddell, Leigh B. , Cole, Andrew D. , Hayward, Christopher , Keogh, Anne , Macdonald, Peter , Griffiths, Lyn , Fatkin, Diane , Sholler, Gary F. , Zorn, Aaron M. , Feneley, Michael P. , Winlaw, David S. , Harvey, Richard P. 
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950799/
https://ncbi.nlm.nih.gov/pubmed/17668378
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