Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging

BACKGROUND: Cell division occurs during normal human development and aging. Despite the likely importance of cell division to human pathology, it has been difficult to infer somatic cell mitotic ages (total numbers of divisions since the zygote) because direct counting of lifetime numbers of divisio...

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Detalhes bibliográficos
Main Authors: Chu, Michelle W, Siegmund, Kimberly D, Eckstam, Carrie L, Kim, Jung Yeon, Yang, Allen S, Kanel, Gary C, Tavaré, Simon, Shibata, Darryl
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950491/
https://ncbi.nlm.nih.gov/pubmed/17672908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-50
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