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Efficient gene transfer by a human immunodeficiency virus type 1 (HIV-1)-derived vector utilizing a stable HIV packaging cell line

By transfecting fibroblast cells with an HIV-1-MN molecular clone with a deletion of the major packaging sequence, we have developed a stable HIV-1 packaging cell line, Ψ422. Ψ422 cells form syncytia with CD4-positive cells, correctly express HIV-1 structural proteins, and produce a large amount of...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Corbeau, Pierre, Kraus, Günter, Wong-Staal, Flossie
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19496/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943062/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.14070
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